Chemical name:
(1,3-dimesitylimidazolidin-2-ylidene)dichloro(2-isopropoxy-5-nitrobenzylidene)ruthenium(II)
Product number:
AS2032
CAS number:
502964-52-5
Patent number:
PCT/EP2003/011222
Universal catalyst which provides good results in a wide spectrum of transformations. High selectivity in cross metathesis (CM) reactions between type 1 olefins (rapid homodimerization, homodimers consumable) and an electron deficient partner, but gives lower efficiency (defined as Turnover Number, TON) than nitro-Grela-SIPr in this type of reactions. More efficient than other catalysts presented herein in reactions with sterically demanding substrates. Comparison with competing products:
– RCM: It is possible to perform the reaction at lower temperature (0 °C). Hoveyda-Grubbs II require higher temperature.
– En-yn: using nitro-Grela gives higher conversion with 2.5 times lower loading catalyst than Hoveyda-Grubbs,
– CM: nitro-Grela allows to perform reaction at lower temperature, with lower loading than Grubbs-II and Hoveyda-Grubbs II. The desired products are obtained with higher selectivity.
Chemical formula: 
C31H37Cl2N3O3Ru
Molecular weight: 671.62 g/mol
Physical state: powder
Color: green
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High stability allows catalyst handling on air.
Long-term storage (>1 week): Store under inert gas in a cold place (recommended temp. 2 – 8 oC).
Short-term storage (<1 week): Store under inert gas at ambient temperature.