We are excited to have an opportunity to share information on Apeiron’s core technology through free webinar. This presentation given by our Senior Research Manager Dr. Anna Gawin will be held on March 27th, 2019 and will start at: 3.00 pm (UK), 4.00 pm (Central Europe) and 10.00 am (East Coast US).
The entire online speech will be dedicated to metathesis, will commence with an explanation of the basic concepts, description of the background of metathesis, then threads concerning benefits enabled by catalytic olefin metathesis as a revolutionary and powerful tool will be raised, as well as new trends and commercial applications in this field.
We encourage you to join us and deepen your knowledge!
Register now, here
The article written by S. Masuda et al. has been recently published on journal Organic & Biomolecular Chemistry, showing the results of their research on the synthesis of unprotected peptides in water by ring-closing metathesis (RCM).
Although RCM is an attractive reaction for the preparation of artificially designed peptides, the article entitled “Ring-closing metathesis of unprotected peptides in water” was the very first report of the possibility of unprotected peptides synthesis in water in the presence of Mg (II) ions, without the addition of any organic solvents in RCM which was achieved using a water-soluble ruthenium catalyst – AquaMet, produced by Apeiron Synthesis.
Authors have carried out the optimization of the reaction conditions and showed that the addition of MgCl2 and/or the use of acidic conditions enables the efficient RCM of unprotected model peptides and octreotide analogues in water. That proposed method, the first non-disulphide type connection reaction between homo functionalities in water, with the usage of our catalyst could become a cornerstone of artificial bioactive peptide mimetics development in future.
The full version of article available: here
From February 11-14, 2019 senior technical representatives of Apeiron Synthesis – Anna Gawin and Andrzej Tracz will be present at the premiere edition of Specialty & Custom Chemicals America trade fair which will take place in the charming and captivating with its Western heritage City of Cowboys and Culture, Fort Worth, located in the center of the Texas State.
This event will focus on the products and technologies that find applications across a various range of specialty and custom chemical end-uses including: agriculture and crop protection, pharmaceuticals, flavors and fragrances, plastics and composites, polymers, monomers, cosmetics, detergents, adhesives, sealants, resins, fuels, biofuels and lubricants, as well as mining and mineral processing.
Trade shows exhibitors and attendees will have opportunities to gain new contacts and to build business relationships with existing and new partners on the new point on the map of events associating together specialists of the chemical industry.
We cordially invite you to visit our exhibit space No. 711 where our staff will be happy to provide you with detailed information about products and services offered by Apeiron Synthesis.
We are pleased to announce that our CTO Krzysztof Skowerski will represent Apeiron with lecture on Stable Carbene Symposium, which will take place on the November 30th, 2018 in Toulouse, France at the University Paul Sabatier (Auditorium Marthe Condat). This event is organized on the occasion of the 30th anniversary of the stable carbenes discovery.
Prolongly regarded as chemical curiosities since they defy the octet rule, carbenes have become common functional groups. Due to their unique properties and broad range of possible applications in homogeneous catalysis, both as organocatalysts and as ligands for transition metals they are considered as one of the most valuable tools in organic, inorganic and organometallic chemistry. They are also increasingly applicable in medicinal chemistry and material science.
This symposium is aiming to gather chemists working on or interested in stable carbenes, and to promote exchange on the developments in carbene chemistry and share researchers latest results. Symposium agenda will consist of nine lectures given by prominent invited speakers. We are proud that Krzysztof Skowerski is also included in this list of the experts of the field.
We are delighted to announce that our products had been placed in Merck’s worldwide catalogue. MERCK KGaA, who acquired Sigma Aldrich is a reputable, globally-expanded company, aiming to “solve the toughest problems in life science by collaborating with the global scientific community” and we are happy to work with them as our products distributor. Currently available catalysts in Merck’s offer are as follows: Nitro-Grela, Nitro-Grela 1. generation, nitro-Grela SI -o-Tolyl, nitro-Grela-I2, GreenCat iPr, AquaMet, StickyCat PF6 and metal scavenger SnatchCat.
This introduction makes our olefin metathesis process promptly accessible to chemists around the world, which allow them to take advantages created by this valuable and efficient catalytic technology, applicable in a broad-spectrum of industries. Usage of our catalysts provides a competitive edge over the conventional methods of synthesizing molecules including, among others, lower catalyst loading and volume of solvent, higher reaction concentrations, reduced amount of by-products and wastes, easy post-reaction ruthenium removal – providing time and money saving solutions.
Now we are working together on implementation of some additional metathesis catalysts. In the near future we are expecting Merck’s offer of Apeiron’s catalysts to be broader.
Apeiron Synthesis is glad that Merck will contribute towards spreading our company’s mission of transforming chemistry!