nitro-Grela-I2 SIPr

Chemical name:

(1,3-bis(2,6-diisopropylphenyl)imidazolidin-2-ylidene)diiodo(2-isopropoxy-5-nitrobenzylidene)ruthenium(II)

Product number:

AS2053

CAS number:

1874265-00-5

Patent number:

PCT/EP2003/011222

Excellent for CM of terminal, type 1 olefins. Provides improved selectivity in metathesis of substrate bearing unprotected -OH and -COOH groups. Very good for RCM with sterically non-demanding substrates leading to small/medium rings. Less sensitive to small impurities than nitro-Grela and nitro-Grela-SIPr.

Distributors
Chemical properties

Chemical formula: 

C37H49I2N3O3Ru

Molecular weight: 938.68 g/mol

Physical state: powder

Color: olive

Questions about the product?
EUROPE

Monika Kulinicz

Sales and Technical Support

monika.kulinicz@apeiron-synthesis.com

Tel.: (+48) 71 798 56 21

NORTH AMERICA

Grazyna Szymanska, PhD

Global Business Development

grazyna.szymanska@apeiron-synthesis.com

Cell: (+1) 781 608 5859

Handling information

High stability allows catalyst handling on air.

Storage information

Long-term storage (>1 week): Store under inert gas in a cold place (recommended temp. 2 – 8 oC).

Short-term storage (<1 week): Store under inert gas at ambient temperature.

Applications

Reference list
  1. T. Nicola, M. Brenner, K. Donsbach, P. Kreye “First Scale-Up to Production Scale of a Ring Closing Metathesis Reaction Forming a 15-Membered Macrocycle as a Precursor of an Active Pharmaceutical Ingredient” Org. Process Res. Dev., 9, 513, (2005).
  2. A. Tracz, M. Matczak, K. Urbaniak, K. Skowerski “Nitro-Grela-type complexes containing iodides – robust and selective catalysts for olefin metathesis under challenging conditions” Belstein J. Org. Chem., 11, 1823, (2015).